Self-esteem, general self-efficacy, and career adaptability, which include career concern, control, curiosity, and confidence, are important resources for adolescents who are required to make important educational and professional choices. No studies have investigated how these resources codevelop over time and their impact on life satisfaction. To more precisely study this codevelopment and the impact of these resources on well-being, 357 Swiss adolescents were assessed 3 times during the last 17 months of compulsory school. The results showed an interrelationship between career adaptability and self-efficacy and a unidirectional effect of self-esteem on life satisfaction over time. They also highlighted the importance of career adapt-ability concerns for predicting the other three career adapt-abilities. Overall, the results suggested that in adolescents, higher levels of career adaptability may favor higher levels of general self-efficacy and that higher levels of self-esteem may induce higher levels of life satisfaction. Implications for practice are discussed.